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I'm in Pfizer's COVID vaccine trial, ask me anything.

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    My wife and I both got our Pfizer shots back in January. Here we are ten months later and the boosters are now available. I got mine the week before Halloween and she was scheduled to get hers this week. Unfortunately, my wife is currently at home knocked on her ass with COVID. It seems we were both exposed at the same time, but she's the one who ended up getting sick. It got to the point where I had to take her to the hospital yesterday. Thankfully, she's back home resting. However, it's apparent that the efficacy of this vaccine does diminish over time. That said, while pretty rough, her fight with COVID could have been far worse had she not been vaccinated. Her history with asthma could have been a death sentence otherwise. Even if you've had your shots, please continue to be careful. If you're eligible to get your booster, get it. I'm living proof that it works. If you haven't gotten any shots at all yet, get off your ass and do it. If more people were vaccinated, we wouldn't be in this mess to begin with.
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      I do volunteer work with HIV+ kids so I'm eligible for the booster, went last Friday and got my flu vaccine and my Pfizer booster. I still generally wear a mask indoors if I'm going to be around a lot of people just in case. Shoot dat science into my veins!
      šŸ’€ PK x Ragnastock šŸ’€

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      • flyweightnate

        flyweightnate

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        I hope they got muscle - there are trials to see whether hitting a vein increases myocarditis risk!

      • Jonnydread

        Jonnydread

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        flyweightnate Yes it was muscle, I was being colorful.

      Originally posted by Jonnydread View Post
      I do volunteer work with HIV+ kids so I'm eligible for the booster, went last Friday and got my flu vaccine and my Pfizer booster. I still generally wear a mask indoors if I'm going to be around a lot of people just in case. Shoot dat science into my veins!
      No concerns of getting COVID boosters and flu vaccines at the same time?

      My pregnant wife wife got her third Pfizer shot last month and was basically bedridden all day the day after. Nothing actually worrying, but she had absolutely zero energy.

      I had the J&J last March and got a Pfizer booster Friday. My arm was pretty sore on Saturday and I felt pretty tired but otherwise was fine. The day after my J&J shot last spring was much worse, probably because I didn't rest.

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      • Jonnydread

        Jonnydread

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        Nope, I rarely have adverse reactions to vaccines and I tend to be foolhardy with my body. I got the two vaccines and played two full days of paintball immediately afterwards. The booster shot site was a wee bit sore, but not bad at all and I didn't have any symptoms. My body seems to be fairly resilient when it comes to medical reactions so I'm fortunate.

      Originally posted by The Inflicted View Post

      No concerns of getting COVID boosters and flu vaccines at the same time?

      ā€‹ā€‹ā€‹ā€‹ā€‹ā€‹
      I had the same thought but the pharmacy said it was fine ...
      Got both of them at the same time, arm was saure for a few days and felt like not too great the same day (but nowhere close as the second shot...)

      Love my brass ... Love my SSR ... Hard choices ...

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      • vijil
        vijil commented
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        We've been officially instructed not to by the NZ Health ministry. 6 week gap at least.

      • XEMON

        XEMON

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        Wired, in Cali they asked me if I wanted it ... Said yes.
        But I didn't ask for it nor mentioned it, the pharmacy brought it up ...

      Got a Moderna booster on top of the Moderna original series two days ago. Much less reaction than with the second original shot. With the 2nd shot I couldn't lift my arm over my head and it hurt like a bugger for nearly a week. The booster was less sore than my flu shot was a few weeks ago.
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        There is currently a report by the LA Times circulating stating that the efficacy of the Moderna vaccine dropped from 89% to 58% by September, the Pfizer vaccine dropped from 87% to 45% effective, and the J&J vaccine dropped from 86% to just 13% effective. However, they don't reveal their sources. How accurate is this data? Anecdotally, the fact that my wife contracted COVID (albeit in a nerfed form compared to the unvaccinated) while I remained unaffected after receiving my booster seems to corroborate this report. Obviously, a two person sample size is woefully inadequate to make any kind of real determination, but it seems to ring true in my case at least.

        This brings me to wonder if pharma companies are continuing to evaluate and improve upon their existing formulas. I'm also wondering how soon boosters will be made available to those outside of the elderly/high-risk groups approved for it currently.
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        • boarder2k7

          boarder2k7

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          FWIW all I had to do to get a booster was click the button on the CVS website, there was no confirmation of status past that. YMMV of course

        I had my pfizer recently. Was gonna lose my job otherwise anyway. Word around here is that efficacy drops to near zero after about 200 days. I'm not sure whether the mrna shots train your system to recognise stuff and react faster in future, as trad vaccines would? Given that the mrna ones shortcut around your system and directly produce the immunity rather than influencing your own system to do that, I can see how it would wane quickly and need boosters. Would each booster last longer? I bloody well hope so.

        But maybe I'm misunderstanding. It's a long thread.

        My experience: it was as though I'd taken a bunch of sleeping pills. Slept for 12 hours afterwards.
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        • JonM

          JonM

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          My wife and I got ours back in January. Here we are in November, I will say that even though she still got COVID recently, her recovery period was significantly faster and her risk of death dropped significantly. I have no doubt that if we were both unvaccinated, she'd be hospitalized right now or worse. So, I'd say it's effectiveness is still way above zero. I'm just thankful I got my booster. I was in direct contact with her and I didn't get so much as a sniffle.

        Had a double whammy today of Flu shot and Booster for Moderna. All went well! Way less of a reaction so far and my arm isn't nearly as bad as the second dose of Moderna. I think my nurse this time was also a stud muffin. I told her to surprise me so I wouldn't subconsciously tense up. Taking maximum strength Tylenol and staying super hydrated. Plus exercise has helped a ton. Went on an hour long walk and did some good ol' work on the house.
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          Happy Thanksgiving everyone! Got a Pfizer booster Monday since it just opened up to my age group (i.e. over 18). Had hoped to mix my original Pfizer shots w a Moderna booster but thatā€™s not how it worked out.

          Booster shot was like the second shot - sore joints and foggy brain and fatigue for a day, then back to normal. On to family and food!
          Originally posted by Chuck E Ducky:
          ā€œYou donā€™t need a safety keep your booger hook on the bang switch.ā€‹ā€œ

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            Well, interesting update for y'all.

            1yo caught COVID at daycare. Couple of days later 3.5yo tested positive. And now five days after that, Abby and I are positive.

            Everyone's fine. 1yo is already her old self. Worst she got was extra tired and maybe a little achy, one rough night of sleep. 3.5yo is extra tired and a bit achy. Abby and I (both have 3 Pfizer doses) are fine so far, but it's early so we'll see. Probably get a bit of a cold, maybe some flu-like symptoms. That's what I'm expecting in the next few days.

            Moral of the story: The pandemic isn't over, get your 3rd doses if you haven't. We likely won't ever know for sure, but I'd bet this is Omicron. It's really early in this wave, so the data is limited, but *so far*, it looks like 2 Pfizer doses will do a really good job protecting against severe illness from Omicron, but not a great job preventing infection. Some protection, but not as much as any other variant. Estimates I've seen range from about 20% to about 70%, compared to 90%+ for everything else. That's for 2 doses. We don't have data on 3 doses yet, but given the information so far with 2, it sure looks like 3 will reduce infection somewhat, and do a really solid job against severe illness.

            So get your shots, y'all. We're not done with this yet.

            How's everyone else doing?

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            • un2xs
              un2xs commented
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              Is there enough data yet to tell if this is going to be a yearly vaccine similar to flu shots?

              What are the studies indicating about the safety of the vaccine? Last I saw there were indications that the MRNA shots are safer than most of the existing vaccines.

            • Diomedes

              Diomedes

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              mRNA vaccines are in fact safer than most other types of vaccines. There's just less stuff in them, so less chance of an adverse reaction.

            Dan, Glad you and the family are weathering well. I'm due for my 3rd dose of Moderna and will be getting it ASAP. I'm unfortunately stuck in an area, where a big portion of the general population, refuses to take this pandemic and precautionary public safety measures seriously.
            Last edited by Carp; 12-11-2021, 03:16 PM.
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              Well, this really sucks. Despite receiving all three shots (or perhaps because of it), I've been dealing with horrendous tinnitus since before Thanksgiving. It's hard to say whether it's a side effect of the Pfizer booster or if it's related to my exposure to COVID from when my wife got it around the same time I got the shot. As best as the ENT can say, tinnitus is a possible side effect of either one. I've been on multiple rounds of steroids, antidepressants, anti-inflammatory meds, and now I'm scheduled to be fitted for hearing aids to hopefully mask the incessant loud 24/7 screaming in my head.
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              • JonM

                JonM

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                Unfortunately the hearing aids didnā€™t help, so they referred me to a tinnitus specialist for CBT. Iā€™ve been sleeping with white noise (or trying to anyway) since this started. Itā€™s better than it was at first so long as I donā€™t trigger a spike, but itā€™s still pretty bad at times and it never goes away.

              • un2xs
                un2xs commented
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                Jon, I wish you well in dealing with this. Tinnitus isn't always easy to deal with... Mine is associated with Menieres Syndrome, which is the umbrella term for a group of symptoms that defy normal classifications.

                I have had tinnitus for at least thirty years... along with dizziness, cognitive lapses and occasional fluctuating hearing. It CAN be lived with. It may take you a bit, but you may be able to ignore it as some of us can. Is yours bilateral or just in one ear? If unilateral, you can compensate by trying to keep your good ear towards your companions so you hear more clearly.

                You MAY want to wait for your ears to settle down to be fitted with hearing aids. Do what is best in your situation. However... see if the insurance will spring for digital hearing aids. These can be adjusted to cover only the hearing range(s) you which cause you problems. A normal hearing aid amplifies across the board and MAY be more of a problem than no sud at all. Not all insurance groups will cover the more tunable hearing aids.

                I am just a patient, but my understanding is that Mennieres as a whole is still not understood. It can come and go as it pleases. If it is extremely debilitating the patient can be a candidate for destructive surgery. Do this only as a last resort... there used to be a 50% chance if total hearing loss in the affected ear.

                I am hoping that you JUST have the tinnitus. It's bad enough without the rest of the symptoms family. If you are lucky it will just go away. Good luck with your recovery. Oh, if you get dizzy, try Meclizine as it can help some with motion sickness.

              • JonM

                JonM

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                It started out in just the right ear, but migrated to both. This and the timing is what convinced the ENT that my symptoms are likely a result of exposure to COVID-19 and/or related to my body's reaction to the Pfizer booster. It's uncommon, but not unheard of. At least the vaccine worked so far as limiting other more dangerous symptoms. This theory is further supported by how much difference heavy steroids and other anti-inflammatory meds made compared to how bad it was at first. Hopefully this is a sign that this may be a temporary situation that may someday resolve itself as the strength of the vaccine wanes and/or my body fights off the infection in my auditory system. Only time will tell.

                My wife also filed a VAERS report so that this symptom can be tracked as a possible side effect.

              Originally posted by JonM View Post
              Well, this really sucks. Despite receiving all three shots (or perhaps because of it), I've been dealing with horrendous tinnitus since before Thanksgiving. It's hard to say whether it's a side effect of the Pfizer booster or if it's related to my exposure to COVID from when my wife got it around the same time I got the shot. As best as the ENT can say, tinnitus is a possible side effect of either one. I've been on multiple rounds of steroids, antidepressants, anti-inflammatory meds, and now I'm scheduled to be fitted for hearing aids to hopefully mask the incessant loud 24/7 screaming in my head.
              As someone who lives with it since birth. I
              can't imagine suddenly having it cursed upon you one day. I only hear it when it acts up and go really loud every now and again or after loud music. Since its always been their since i can remember its background noise at best in a completely quite room. But i know no alternative to it, its just normal sounding and not annoying to me.

              Bummer man

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              • JonM

                JonM

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                Yeah. I've already had several nervous breakdowns as a result of it. In my case, it's always on. I'm just hoping that if it's COVID or booster related that it will eventually go away (although I'm not holding my breath). Hopefully the hearing aids will help during the day at least. Nighttime is another matter. I've needed white noise and sleeping pills to get more than a few hours per night.

              Finally got my 3 shot of Moderna this morning and so far, only a little sore around the injection site. But, that's to be expected. šŸ˜‰


              Diomedes How are you and the family holding up?
              ā€‹ā€‹ā€‹ā€‹ā€‹ā€‹ā€‹
              JonM Any reprieve with the tinnitus yet?
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              • JonM

                JonM

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                Unfortunately not. Iā€™m seeing a specialist next month since the hearing aid fitting yielded no improvement. All reports from others who have reported similar side effects seem to indicate a lengthy recovery period (if it ever resolves at all- not enough data and little to no research).

              • Diomedes

                Diomedes

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                We're all good. Kids are past their 10 days, and were completely recovered after just a few days each more tired than normal. I had a cold for a couple of days, have a stuffy nose as I type this, otherwise fine, and Abby got the worst of it with a mild flu for about two days and lost taste and smell, but she's better except for taste and smell, which are coming back slowly. Overall...whole family got COVID and came through fine, so can't really complain. Tomorrow (12/20) is our last day of quarantine, can't wait to be done.

              • JonM

                JonM

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                That's good to hear. My wife got her senses of taste and smell back a few weeks after her bout with breakthrough COVID. Although, she's still dealing with long haul symptoms herself. Between her coughing fits and my tinnitus (which is even further aggravated by the coughing), we're not exactly happy campers.

              Aww man, so lets resurrect a living ghost.

              My wife just had Covid for a week, she was mildly sick, but feels better today. She was due to get her booster last Friday, and fell ill a few days prior.

              She has the pfizer vax, I went with Moderna.

              Well as of the first of the year my work changed their policy to adhere to the CDC essentially stating I dont need to quarantine if exposed to Covid if I have up to date vaccinations. Mine are "good" til Feb 16th. Where as 2 weeks ago, Id have a paid vacation for quarantine if it was even thought I was exposed.

              A co worker of mine also had a wife who tested positive the same day. We both reported it to HR, and were told we can keep working as long as we feel not sick. We both felt fine. And he tested negative twice. I cant find testing appts near me. So I went off of feel.

              Now at work. Its a stay home if sick policy regardless of positive covid test of not half of the shop had been hacking up a lung since Chrustmas. And one electrician specifically whom I help a lot, he has been really under the weather for the past three days. And working. I kept telling him to just go home or get tested. Today he left sick at start. Annnd tested positive.

              Annnd now Im starting to feel run down today, and only worked 8hours ratger than my typical 10.

              I am supposed to work tomorrow and Sunday too.


              But my wife is going ro get an at home test from a family friend tonight so tgeres a chance im negative and a nice sleep will fix me up, but Im thinking my odds are I got it.


              So now I lay here kind of mad at my employer as I feel the dropping of the qurrantine window for first degree exposure is and was a poor move.

              Whos to tell how bad it spread at work at this point.

              All in all it just seems like a regular flu so far for me.
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